The development of improved methods for genome‐wide association studies (GWAS) for genetics of quantitative traits has been an active area of research during the last 25 years. This activity initially started with the use of mixed linear model (MLM), which was variously modified. During the last decade, however, with the availability of high throughput next generation sequencing (NGS) technology, development and use of pangenomes and novel markers including structural variations (SVs) and k‐mers for GWAS has taken over as a new (...) thrust area of research. Pangenomes and SVs are now available in humans, livestock, and a number of plant species, so that these resources along with k‐mers are being used in GWAS for exploring additional genetic variation that was hitherto not available for analysis. These developments have resulted in significant improvement in GWAS methodology for detection of marker‐trait associations (MTAs) that are relevant to human healthcare and crop improvement. (shrink)

Sustainable behaviour promotes pro-ecological behaviour and is a practice of consuming and utilizing resources responsibly. The ongoing COVID-19-induced pandemic has already put economic, social and psychological distress across the globe. Meanwhile, it has become vital to think of issues related to the sustainable management of resources. Behavioural norms play a prominent role while promoting sustainable living. This research examines how the sustainable dimension in one’s behaviour influences the decision-making in their daily life. Previous studies have shown the importance of sub-factors (...) like happiness, diversity constraint and frugal actions as factors affecting sustainable behaviour. These indicators mainly define the action one will choose to react to while buying and consuming different resources. The study identifies happiness as the mediating variable which influences the relationship between the predictor variables—mindfulness and diversity acceptance and the criterion variable—frugality-linked sustainable behaviour. With a sample of 324 participants, Baron and Kenny’s mediation model was outlined to test the mediation. Results showed a positive relationship between frugality, diversity, mindfulness and happiness. Happiness was found to be mediating between mindfulness, diversity acceptance and frugality-linked sustainable behaviour indicating that mindfulness and diversity acceptance alone have limited potential to impact the frugality-linked sustainable approach that individuals take. Happiness, as explained through a positive frame of mind, plays a very important role in enhancing sustainability behaviour. (shrink)

The earlier volume in this series dealt with two religions of Indian origin, namely, Buddhism and Jainism. The Indian religious scene, however, is characterized by not only religions which originated in India but also by religions which entered India from outside India and made their home here. Thus religious life in India has been enlivened throughout its history by the presence of religions of foreign origin on its soil almost from the very time they came into existence. This volume covers (...) three such religions—Zoraoastrianism, Judaism, and Islam. In the case of Zoraostianism, even its very beginnings are intertwined with India, as Zoroastrianism reformed a preexisting religion which had strong links to the Vedic heritage of India. This relationship took on a new dimension when a Zoroastrian community, fearing persecution in Persia after its Arab conquest, sought shelter in western India and ultimately went on to produce India’s pioneering nationalist in the figure of Dadabhai Naoroji ( 1825-1917), also known as the Grand Old Man of India. Jews found refuge in south India after the destruction of the Temple by the Romans in 70 C.E. and have remained a part of the Indian religious scene since then, some even returning to Israel after it was founded in 1948. Islam arrived in Kerala as soon as it was founded and one of the earliest mosques in the history of Islam is found in India. Islam differs from the previously mentioned religions inasmuch as it went on to gain political hegemony over parts of the country for considerable periods of time, which meant that its impact on the religious life of the subcontinent has been greater compared to the other religions. It has also meant that Islam has existed in a religiously plural environment in India for a longer period than elsewhere in the world so that not only has Islam left a mark on India, India has also left its mark on it. Indeed all the three religions covered in this volume share this dual feature, that they have profoundly influenced Indian religious life and have also in turn been profoundly influenced by their presence in India. (shrink)

Introduction: Decisions to withdraw or withhold curative or life-sustaining treatment can have a huge impact on the symptoms which the palliative-care team has to control. Palliative-care patients and their relatives may also turn to palliative-care physicians and nurses for advice regarding these treatments. We wanted to assess Indian palliative-care nurses and physicians’ attitudes towards withholding and withdrawal of curative or life-sustaining treatment. Method: From May to September 2008, we interviewed 14 physicians and 13 nurses working in different palliative-care programmes in (...) New Delhi, using a semi-structured questionnaire. For the interviews and analysis of the data we followed Grounded-Theory methodology. Results: Withholding a curative or life-sustaining treatment which may prolong a terminal cancer patient’s life with a few weeks but also has severe side-effects was generally considered acceptable by the interviewees. The majority of the interviewees agreed that life-sustaining treatments can be withdrawn in a patient who is in an irreversible coma. The palliative-care physicians and nurses were of the opinion that a patient has the right to refuse life-saving curative treatment. While reflecting upon the ethical acceptability of withholding or withdrawal of curative or life-sustaining treatment, the physicians and nurses were concerned about the whole patient and other people who may be affected by the decision. They were convinced they can play an important advisory role in the decision-making process. Conclusion: While deciding about the ethical issues, the physicians and nurses do not restrict their considerations to the physical aspects of the disease, but also reflect upon the complex wider consequences of the treatment decisions. (shrink)

This study examines the notion of 'spirituality' as a dimension of human self, and its relevance and role in management. Major thesis of this research is that spirituality of employees is reflected in work climate. This may in turn affect the employees' service to the customers. In the first part of the study a Spiritual Climate Inventory is developed and validated with the data from manufacturing and service sector employees. In the later part, hypothesis of positive impact of spiritual climate (...) on customers' experience of employees' service is examined and found to be substantiated empirically. (shrink)

A natural realist approach to the philosophy of arithmetic is defended by way of considering and arguing against contemporary attempts to solve Paul Benacerraf's dilemma . The first horn of the dilemma concerns the existence of abstract mathematical objects, which seems necessitated by a desire for a unified semantics. Benacerraf adopts an extensional semantics whereby the reference of terms for natural numbers must be abstract objects. The second horn concerns a desirable causal constraint on knowledge, according to which "for X (...) to know that S is true requires some causal relation to obtain between X and the referents of the names, predicates, and quantifiers of S". Within the philosophical tradition, Benacerraf's dilemma crystallizes the tension between realists and empiricists . It is shown that natural realism and naturalism meet. ;Both horns of the dilemma are amended.objects are conceived along conceptualist lines such that their existence is not mind-independent. The causal constraint is refined by drawing upon the work of Mark Steiner . Natural realism is the notion that the truth-values of arithmetical statements are recognition-transcendent. Natural realism explains why one and only one arithmetic is applicable. It is in some sense discovered, which is captured by the idea that arithmetical statements have truth-values even if one is not able to adduce what they are. ;It is argued that with proper emendation, like that of Philip Kitcher , empiricism as envisioned by J. S. Mill is defensible. Furthermore, the epistemology of arithmetical knowledge is divided into two tiers. The first principles of arithmetic are acquired by causal interaction with physical objects. As Kitcher has shown, empiricism functions at the first-tier. The a priori is revised such that arithmetical knowledge generated from the first-tier is considered non-empirical. ;It is argued that pragmatists' indispensability argument, once qualified, allows that arithmetic's applicability is one reason to consider natural realism for that domain . Furthermore, this thesis provides a case where aspects of Hilary Putnam's early and later views are rendered consistent. By way of utilizing both Putnam's writing in favour of realism , and those that break with them , it is suggested that he should not have abandoned his earlier view. In a nutshell, the realization of knowledge can depend upon agents' values, methods, and so on, without forcing the abandonment of realism . Putnam's early view sets the criteria for when one can be a realist about a given domain. (shrink)

The marketing culture is essential for improving performance in the highly competitive restaurant industry. It investigates the effectiveness of marketing culture dimensions on the performance of restaurants in the competitive restaurant industry. The data was gathered from 298 respondents of managers and employees across 48 restaurants using a structured questionnaire. Partial Least Squares Structural Equation Modeling (PLS-SEM) was used to evaluate the connections between these constructs. The measurement model assessment was validated using indicators such as Average Variance Extracted (AVE), Composite (...) Reliability, and Cronbach’s Alpha. The structural model assessment investigation's strategy hypothesized connections were also tested using evaluations of five structural path frameworks. The findings demonstrate that all five dimensions of marketing culture positively and significantly impact restaurant performance. Sales strategy had the strongest influence, followed by innovation potential, quality of service, organizational structure, and leadership-staff collaboration. All hypothesized relationships were supported with significant path coefficients, T-values, and p-values. The study emphasizes the importance of a robust marketing culture in enhancing restaurant performance and suggests that restaurant managers should prioritize the development of effective sales strategies and foster innovation within their marketing culture. (shrink)

The presence of vegetation on railway tracks threatens track safety and longevity. However, vegetation inspections in Sweden are currently being carried out manually. Manually inspecting vegetation is very slow and time consuming. Maintaining an even quality standard is also very difficult. A machine vision-based approach is therefore proposed to emulate the visual abilities of the human inspector. Work aimed at detecting vegetation on railway tracks has been split into two main phases. The first phase is aimed at detecting vegetation on (...) the tracks using appropriate image analysis techniques. The second phase is aimed at detecting the rails in the image to determine the cover of vegetation that is present between the rails as opposed to vegetation present outside the rails. Results achieved in the current work indicate that the machine vision approach has performed reasonably well in detecting the presence/absence of vegetation on railway tracks when compared with a human operator. (shrink)

Secularization of life in general is widely seen as a direct consequence of European enlightenment and the process of modernization. The paper contests this thesis of societal secularization through a historical analysis of ideas in the Anglo-Saxon Christian parts of Europe and North America. It contends that the sense of the sacred has either been pushed to the private lives of individuals or marginalized into myriad forms of counter-movements. This paper then contests secularization of organizations and sees it as a (...) thin veil of misperception. Success of Japanese organizations and studies thereof, have brought back the inevitable relevance of societal cultures for organizational management. A sense of the sacred is an essential aspect of culture—societal or organizational—which must be taken into account to build truly humane and optimally effective organizations. The theory and practice of organization development must advance itself accordingly to remain true to its spirit. (shrink)

The article discusses the meaning of consciousness and presents a collective consciousness view of business organizations and their development. It proposes an integrative hierarchical framework of three levels of organizational consciousness: material, social and spiritual. The concepts of excellence, ethical and moral temperament of organizations at different levels of consciousness are also discussed. The article describes the features of social and spiritually conscious business organizations, taking some examples from secondary sources. Overall, it is an attempt to link the ideals of (...) human evolution with the potential behaviour of business corporations. (shrink)

Substantive scientific letter writing is a cost-effective mode of complementing observational and experimental research. The value of such philosophically uncommitted and unsponsored well-balanced scientific activity has been relegated. Critical letter writing entails the abilities to: maintain rational scepticism; refuse to conform in order to explain data; persist in keeping common sense centre-stage; exercise logic to evaluate the biological significance of mathematical figures, including statistics, and the ability to sustain the will to share insights regarding disease mechanisms on an ostensibly lower (...) research platform. During peer review, innovative letter writing may share the occasionally unfortunate fate of innovative research. Rejected scientific letters do not automatically lose copyright. Periodicals with high letter loads will see some valuable contributions wasted, but that is the price for maintaining autonomy in scientific publication. The scientific community is an integrated whole that must respect the rights of authors at all levels. Unauthorised forwarding of rejected letters sets the dangerous precedent of justifying unjust means. (shrink)

This book explores the apostle Paul’s temple, priesthood, sacrificial, and worship language with a special interest in how metaphors are powerful vehicles for theological transformation. The methodology of this study combines perspectives from cognitive linguistics, the social-sciences, and rhetorical criticism. In the final synthesis, it is discovered that common factors among Paul ’s cultic metaphors include an interest in devotion to God, the significance of the body, and the potential for the reshaping of the mind and perception.

The Yogārṇava is a Sanskrit compendium on yoga that has not been published, translated or even mentioned in secondary literature on yoga. Citations attributed to it occur in several premodern commentaries and compendiums on yoga, and a few published library catalogues report manuscripts of a work on yoga called the Yogārṇava. This article presents the results of the first academic study of the text. It has attempted to answer basic questions, such as the work’s provenance and textual sources. The authors (...) then discuss the importance of the Yogārṇava within the broader history of yoga based on their identification of citations and parallel verses in other Sanskrit texts and a detailed analysis of the Yogārṇava’s content. (shrink)